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COMPOUNDS AS RORyT MODULATORS AND USES THEREOF
专利权人:
Dan Littman;Ruili Huang;Wenwei Huang;Jun R. Huh
发明人:
Dan Littman,Jun R. Huh,Wenwei Huang,Ruili Huang
申请号:
US13634102
公开号:
US20130065842A1
申请日:
2011.03.11
申请国别(地区):
US
年份:
2013
代理人:
摘要:
Heterocyclic compounds, and pharmaceutical compositions thereof, are disclosed as RORγt modulators that have a formula represented by the following:and wherein n1, n2, R1, R2, R3, and R4 are as described herein. These compounds may be used for the prevention and treatment of a variety of conditions in mammals including humans, including by way of non-limiting example, inflammatory conditions, autoimmune disorders, cancer, and graft-versus-host disease.
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