METCALF, Brian,CHUANG, Chihyuan,WARRINGTON, Jeffrey,PAULVANNAN, Kumar,JACOBSON, Matthew P.,HUA, Lan,MORGAN, Bradley
申请号：
DK12862525
公开号：
DK2797416T3
申请日:
2012.12.28
申请国别(地区):
DK
年份:
2017
代理人:
摘要：
Provided are substituted benzaldehydes and derivatives thereof of formula (I) that act as allosteric modulators of hemoglobin, methods and intermediates for their preparation, pharmaceutical compositions comprising the modulators, and methods for their use in treating disorders mediate by hemoglobin and disorders that would benefit from increased tissue oxygenation.
