David S. Soane,Robert P. Mahoney,Philip Wuthrich,Daniel G. Greene
申请号：
US16789803
公开号：
US20200316196A1
申请日:
2020.02.13
申请国别(地区):
US
年份:
2020
代理人:
摘要：
The invention encompasses injectable therapeutic formulations for injection into patients in need thereof, wherein the injectable formulations are injected using a medical device having a hydrophobic surface； the injectable therapeutic formulation comprises a therapeutic protein and a stabilizing excipient that protects the therapeutic protein from forming particulates or aggregates in the presence of the hydrophobic surface. Also included are methods for reducing particulates or aggregates by using such injectable therapeutic formulations in medical devices having hydrophobic surfaces.
