(S)-N-METIL-8-(1-((2`-METIL-[4,5`-BIPIRIMIDIN]-6-IL)AMINO)PROPAN-2-IL)CHINOLIN-4-KARBOKSAMIDO IR JO DEUTERINTŲ DARINIŲ, KAIP DNR-PK INHIBITORIŲ, BENDRI KRISTALAI

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专利权人:

Vertex Pharmaceuticals Incorporated

发明人:

NTI-ADDAE, Kwame,O,NEIL, Simon,ZHANG, Yuegang,MUDUNURI, Praveen,VAN ALSTEN, John Gregg,SONG, Bin,STAVROPOULOS, Kathy,STROHMEIER, Mark,WALDO, Michael,NAVAMAL, Mettachit,KADIYALA, Irina Nikolaevna,STAVRO

申请号：

LT14799578

公开号：

LT3057953T

申请日:

2014.10.17

申请国别(地区):

LT

年份:

2018

代理人:

摘要：

The present invention relates to compositions and co-crystals each comprising a compound of formula I having the structure: wherein each of R 1 and R 2 is H or 2 H and a co-crystal former selected from adipic acid, citric acid, fumaric acid, maleic acid, succinic acid, or benzoic acid. Also within the scope of this invention are methods of making and using the same.

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来源网址：

http://www.ckcest.cn/home/