KOKRISTALI (S)-N-METIL-8-(1-((2'-METIL-[4,5'-BIPIRIMIDIN]-6-IL)AMINO)PROPAN-2-IL)HINOLIN-4-KARBOKSAMIDA I NJIHOVI DEUTERISANI DERIVATI KAO INHIBITORI DNK-PK

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专利权人:

VERTEX PHARMACEUTICALS INCORPORATED

发明人:

NTI-ADDAE, KWAME, WIREDU,O'NEIL, SIMON, ADAM,ZHANG, YUEGANG,MUDUNURI, PRAVEEN,VAN ALSTEN, JOHN, GREGG,SONG, BIN,STAVROPOULOS, KATHY,STROHMEIER, MARK,WALDO, MICHAEL,NAVAMAL, METTACHIT,KADIYALA, IRINA,

申请号：

RSP20200607

公开号：

RS60426B1

申请日:

2014.10.17

申请国别(地区):

RS

年份:

2020

代理人:

摘要：

The present invention relates to compositions and co-crystals each comprising a compound of formula I having the structure: wherein each of R 1 and R 2 is H or 2 H and a co-crystal former selected from adipic acid, citric acid, fumaric acid, maleic acid, succinic acid, or benzoic acid. Also within the scope of this invention are methods of making and using the same.

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中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/