Pasquale FORGIONE,Alisa Julienne PIEKNY,Dilan Boodhai JAUNKY,Fei CHEN,Jiang Tian LIU
申请号:
US16465966
公开号:
US20200024284A1
申请日:
2017.12.06
申请国别(地区):
US
年份:
2020
代理人:
摘要:
The present disclosure relates to fused N-arylsulfonamidyl-thienoisoquinoline compounds, derivatives and pharmaceutical compositions thereof, and methods and uses in inhibiting cancer cell growth, along with a supplemental anti-cancer agent. Centrosome targeting and microtubule depolymerisation are attractive in designing the present chemotherapeutic compounds. The various diseases and conditions treated include various types of cell cancers, and in vitro inhibition.