1. Use of a compound for the manufacture of a medicament for treating a disease or condition of the eye, wherein the compound has the formula: where R represents a substituted or unsubstituted thiazolyl moiety having the formula: or or R, each independently represent a: i) hydrogen ii) substituted or unsubstituted C Clineyny, C-Crazvetvlenny or C-Ctsiklichesky alkyl iii) substituted or unsubstituted C Clineyny, C-Crazvetvlenny or C-Ctsiklichesky alkenyl iv) substituted or unsubstituted C-Clineyny or branched alkynyl v ) replaced whelping or unsubstituted C or Saril vi) substituted or unsubstituted C-Cgeteroaril vii) substituted or unsubstituted C-Cgeterotsikl iliviii) may be the r and taken together to form a saturated or unsaturated ring having from 5 to 7 atoms wherein from 1 to 3 atoms may optionally be heteroatoms selected from oxygen, nitrogen and sulfur Z is a moiety having the formula: R c is selected from: i) hydrogen ii) hydroxyl iii) amino iv) substituted or unsubstituted C-Clineynogo , C-Crazvetvlennogo Ctsiklicheskogo or C-alkyl v) substituted or unsubstituted C Clineynogo, C-Crazvetvlennogo Ctsiklicheskogo or C-alkoxy vi) substituted or unsubstituted C or Sarila vii) substituted or unsubstituted C-Cgeterotsiklicheskih rings iliviii) substituted or unsubstituted C-Sgeteroarilnyh ring L represents a linking moiety having the formula: - [Q] [C (RR)] [Q] (C (RR)] -, Q and Qkazhdy independently is: i) - C (O) - ii) -NH- iii) -C (O) NH- iv) -NHC (O) - v) -NHC (O) NH- vi) -NHC (O) O- vii) -C (O) O- viii) -C (O) NHC (O) - ix) -O- x) -S- xi) -SO- xii) -C (= NH) - xiii) -C (= NH) NH- xiv) -NHC (= NH) - ilixv) -NHC (= NH) NH- r and are each is independently: i) hydrogen ii) hydroxy iii) halogen iv) substituted or unsubstituted
