Margaret Phillips,Pradipsinh K. Rathod,Ramesh Gujjar,Alka Marwaha,Susan A. Charman
申请号：
US12339905
公开号：
US09216983B2
申请日:
2008.12.19
申请国别(地区):
US
年份:
2015
代理人:
摘要：
Compounds according to Formula I, Formula II, Formula III, Formula V, Formula VI, or to Formula VII,and pharmaceutical compositions of compounds that conform to Formula IV or Formula VIII:where R1 through R33 are prescribed, selectively inhibit P. falciparum dihydroorotate dehydrogenase. Accordingly, a method for preventing and treating malaria attaches to such compounds, as well as to pharmaceutically acceptable salts, solvates, stereoisomers, tautomers, and prodrugs thereof.
