Max-Planck-Gesellschaft-zur-Förderung der Wissenschaften e.V.
发明人:
Gregor Eichele,Henrik Oster,Silke Kiessling
申请号:
US14573638
公开号:
US09770444B2
申请日:
2014.12.17
申请国别(地区):
US
年份:
2017
代理人:
摘要:
The present invention relates to a modulator of glucocorticoid biosynthesis, degradation and/or receptor activation for use in preventing or treating symptoms and/or diseases associated with jet lag. The compositions of the invention may be used as a lead compound for developing a drug for preventing or treating symptoms and/or diseases associated with jet lag. The invention relates to the discovery that administration of the modulator(s) to a subject results in a directional change of the time point of maximum amounts of glucocorticoids in the subject as compared to the time point of maximum amounts of glucocorticoids in a subject not treated with the modulator(s).