ALKAHEST INC.;BOEHRINGER INGELHEIM INTERNATIONAL GMBH
发明人:
申请号：
IL23426214
公开号：
IL234262A
申请日:
2014.08.24
申请国别(地区):
IL
年份:
2017
代理人:
摘要：
The present invention relates to CCR3 inhibitors of formula 1, wherein R1 is H, C1-6-alkyl, C0-4-alkyl-C3-6-cycloalkyl, C1-6-haloalkyl； R2 is H, C1-6-alkyl； X is an anion selected from the group consisting of chloride or ½ dibenzoyltartrate j is 1 or 2. for use as a medicament for the treatment of diseases selected from dry age-related macular degeneration (dAMD), wet age-related macular degeneration (wAMD), retinopathy of prematurity (ROP), central retinal vein occlusion (CRVO), nasal polyposis, eosinophilic esophagitis, eosinophillic gastroenteritis (e.g. eosinophilic gastritis and eosinophilic ententeritis), hypereosinophilic syndrome and Churg Strauss syndrome.
