Donmienne Doen Mun Leung,Peng Luan,Barbara Anne Swanson,Ying Tang,Derrick Ryan Witcher
申请号：
US13708059
公开号：
US08765129B2
申请日:
2012.12.07
申请国别(地区):
US
年份:
2014
代理人:
摘要：
Monoclonal antibodies are provided that selectively bind human hepcidin-25 and are characterized as having high affinity for human hepcidin-25 and strong human mature hepcidin neutralizing properties. The antibodies of the invention are useful therapeutically for increasing serum iron levels, reticulocyte count, red blood cell count, hemoglobin, and/or hematocrit in a human and for the treatment and diagnosis of mature hepcidin-promoted disorders such as anemia, in a human subject.
