Santiago Dueñas Carrera,Daylen Aguilar Noriega,Yalena Amador Cañizares,Liz Alvarez-Lajonchere Ponce de León,Gillian Martínez Donato,Sonia Gonzalez Blanco
申请号：
US14440443
公开号：
US20150307558A1
申请日:
2013.10.28
申请国别(地区):
US
年份:
2015
代理人:
摘要：
The invention relates to chimeric vaccine antigens against hepatitis C virus (HCV) comprising selected regions of different antigens of said virus, which are placed in a pre-determined order inside the polypeptide. In addition, said chimeric antigens can include artificially formed specific epitopes for auxiliary T helper lymphocytes. The chimeric antigens and the resulting vaccine compositions are suitable for use in medicine and the pharmaceutical industry, as well as being suitable for prophylactic and/or therapeutic use against HCV. The vaccine compositions of the invention generate a powerful, broad-spectrum immune response against different antigens of the virus, with a minimum number of components.
