Duenas Carrera, Santiago,Aguilar Noriega, Daylen,Amador Canizares, Yalena,Alvarez-Lajonchere Ponce De Leon, Liz,Martinez Donato, Gillian,Gonzalez Blanco, Sonia
申请号：
AU2013339846
公开号：
AU2013339846B2
申请日:
2013.10.28
申请国别(地区):
AU
年份:
2017
代理人:
摘要：
The invention relates to chimeric vaccine antigens against hepatitis C virus (HCV), comprising selected regions of different antigens of said virus, which are placed in a pre-determined order inside the polypeptide. In addition, said chimeric antigens can include artificially-formed specific epitopes for auxiliary T cells. The chimeric antigens, and the resulting vaccine compositions, are suitable for use in medicine and the pharmaceutical industry, as well as being suitable for prophylactic and/or therapeutic use against HCV. The vaccine compositions of the invention generate a powerful, broad-spectrum immune response against different antigens of the virus, with a minimum number of components.
