Compositions are disclosed for topical treatment of mammalian skin, particularly human skin, relieve the distressing symptoms of the many skin diseases and provide, in many cases, a long term cure. The composition comprise, in combination, one or more boswellic acids and/or a fatty acid having a chain length of at least 18 carbon atoms and which contains at least two unsaturated linkages together with an enzyme based antibacterial system. The compositions will selectively reduce cell turnover and may be used for the treatment of eczema and/or psoriasis.
