COMPOSES PURINE UTILISES EN TANT QUE PROMEDICAMENTS DES ANTAGONISTES DU RECEPTEUR A2B DE L'ADENOSINE, LEUR PROCEDE DE PREPARATION ET LEURS APPLICATIONS MEDICALES
The present disclosure relates to purine compounds of formula (I) or formula(II)(see formula I) (see formula II)or tautomers, polymorphs, stereoisomers, solvates or pharmaceuticallyacceptable saltsthereof, where substituents arc as defined herein, as well as pharmaceuticalcompositionscontaining them and methods of treating conditions and diseases that aremediated by thereofas A2B adenosine receptor antagonists. The compounds of the present disclosuremay beuseful in the treatment, prevention or suppression of diseases and disordersthat may besusceptible to improvement by the mediation of adenosine A2B receptor. Thepresentdisclosure also relates to methods for the preparation of such compounds, andtopharmaceutical compositions containing them.
