High growth reassortant influenza A virus
- 专利权人:
- Thomas Muster
- 发明人:
- Thomas Muster,Markus Wolschek,Andrej Egorov,Elisabeth Roethl,Julia Romanova,Michael Bergmann
- 申请号：
- US13140395
- 公开号：
- US08691238B2
- 申请日:
- 2009.12.18
- 申请国别(地区):
- US
- 年份:
- 2014
- 代理人:
- 摘要：
- The present invention provides a high growth reassortant influenza A virus having at least two gene segments of seasonal or pandemic strain origin, a PB1 gene segment of A/Texas/1/77 strain origin and a PA gene segment of A/Puerto Rico/8/34 (H1N1) origin coding for a PA protein comprising at least one amino acid modification at any one of positions 10, 275, 682, according to SEQ ID No. 1. Further provided are vaccine formulations comprising the reassortant influenza A virus of the invention.
- 来源网站：
- 中国工程科技知识中心
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