Methods and devices for directing a waste fluid from a radiopharmaceutical synthesis system to a waste vessel are provided. In one example, the method includes serially connecting a primary waste vessel to a secondary waste vessel with a fluid conduit, including a waste valve connected to the fluid conduit extending between the primary waste vessel and secondary waste vessel； opening the waste valve so as to allow fluid communication between cavities of the primary and secondary waste vessels； drawing a low pressure in both waste vessels； closing the waste valve so as to fluidically isolate the secondary waste vessel from the primary waste vessel, discharging the waste fluid through a pump valve into the primary waste vessel, and opening the waste valve to evacuate the waste fluid from the primary waste vessel into the secondary waste vessel.La présente invention concerne des procédés et des dispositifs pour évacuer le contenu d'un contenant à déchets primaire dans un contenant à déchets secondaires, de préférence entre des lots de fabrication d'un dispositif de synthèse automatisé.
