Andreas Meinke;Astrid Teubenbacher;Beatrice Senn;Manuel Zerbs;Markus Hanner;Jutta Pikalo;Eszter Nagy;Carmen Giefing-Krōll;Alexander Von Gabain
发明人:
Andreas Meinke,Astrid Teubenbacher,Beatrice Senn,Manuel Zerbs,Markus Hanner,Jutta Pikalo,Eszter Nagy,Carmen Giefing-Krōll,Alexander Von Gabain
申请号:
US12933020
公开号:
US08241643B2
申请日:
2009.03.17
申请国别(地区):
US
年份:
2012
代理人:
摘要:
The present invention relates to a protective peptide of Streptococcus pneumoniae (S. pneumoniae) or a functionally active variant thereof; a composition comprising at least two of such peptides or variants; one or more nucleic acid(s) encoding such peptide or variant; a pharmaceutical composition comprising such peptide or variant, composition, or nucleic acid(s); a method of producing an antibody using such peptide or variant or composition; the use of such peptide or variant and/or composition and/or nucleic acid(s) for the manufacture of a medicament; a method of diagnosing a S. pneumoniae infection using such peptide or variant, composition or a primer and/or probe specific for the nucleic acid(s); a method for identifying a ligand capable of binding to such peptide or variant; and the use of such peptide or variant for the isolation, purification and/or identification of an interaction partner of the peptide.