Andreas Meinke,Astrid Teubenbacher,Beatrice Tschanun,Manuel Zerbs,Markus Hanner,Jutta Pikalo,Eszter Nagy,Carmen Giefing-Kröll,Alexander Von Gabain
申请号:
US13565990
公开号:
US20120294881A1
申请日:
2012.08.03
申请国别(地区):
US
年份:
2012
代理人:
摘要:
The present invention relates to a protective peptide of Streptococcus pneumoniae (S. pneumoniae) or a functionally active variant thereof; a composition comprising at least two of such peptides or variants; one or more nucleic acid(s) encoding such peptide or variant; a pharmaceutical composition comprising such peptide or variant, composition, or nucleic acid(s); a method of producing an antibody using such peptide or variant or composition; the use of such peptide or variant and/or composition and/or nucleic acid(s) for the manufacture of a medicament; a method of diagnosing a S. pneumoniae infection using such peptide or variant, composition or a primer and/or probe specific for the nucleic acid(s); a method for identifying a ligand capable of binding to such peptide or variant; and the use of such peptide or variant for the isolation, purification and/or identification of an interaction partner of the peptide.