The device (10) comprises a mixing cylinder (20) with a mixing piston (21) that is axially moved by an operating rod (50) which is guided outward on a cylinder end (30). A seal piston (42) is arranged in the area of the cylinder end for closing the mixing cylinder in a gas-tight manner. A sterilization piston (41) is arranged in the area of the cylinder end between the mixing piston and the sealing piston. A bone cement powder has a binder, particularly a monomer. An independent claim is also included for a bone cement system with a supply element.
