HIROSHI KAMIYAMA,KAZUHIKO YAMADA,MASAHIRO MATSUKI,YOICHI OZAWA,YUSAKU HORI
申请号：
BR112019014127
公开号：
BR112019014127A2
申请日:
2018.02.06
申请国别(地区):
BR
年份:
2020
代理人:
摘要：
a tumor tumor pharmaceutical composition used in combination therapy of lenvatinib and (6s, 9as) -n-benzyl-8 - ({6- [3- (4-ethylpiperazin-1-yl) azetidin-1- yl] pyridin-2-yl} methyl) -6- (2-fluoro-4-hydroxybenzyl) -4,7-dioxo-2- (prop-2-en-1-yl) hexahydro-2h-pyrazine [ 2,1-c] [1,2,4] triazine-1 (6h) -carboxamide.é proporcionada uma composição farmacêutica para tratamento de um tumor usada em terapia de combinação de lenvatinib e (6s,9as)-n-benzil-8-({6-[3-(4-etilpiperazin-1-il)azetidin-1-il]piridin-2-il}metil)-6-(2-fluoro-4-hidroxibenzil)-4,7-dioxo-2-(prop-2-en-1-il)hexa-hidro-2h-pirazino[2,1-c][1,2,4]triazina-1(6h)-carboxamida.
