Use as melanocortin receptor ligands of benzylideneamino guanidine and hydroxy guanidine

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专利权人:

アナマル エービー

发明人:

ルンドステット、トルビョルン,スコットナー、アンナ,セイフェルト、エリザベス

申请号：

JP2011148414

公开号：

JP5683396B2

申请日:

2011.07.04

申请国别(地区):

JP

年份:

2015

代理人:

摘要：

The present invention relates to the use of compounds of general formula (I) as ligands to the melanocortin receptors and/or for treatment of disorders in the melanocortin system: wherein X is H or OH； R1, R2, R3, R4 and R5 are the same or different and are selected from hydrogen, halogen, alkyl having 1 to 5 carbon atoms, electron donor groups such as alkoxy having 1-5 carbon atoms or hydroxy, electron acceptor groups selected from cyano, nitro, trifluoroalkyl or amide； alkylamino, benzoyloxy, nitroxy, phenyl or sulpho； and the pharmacologically active salts thereof.

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