INDUSTRY-UNIVERSITY COOPERATION FOUNDATION HANYANG UNIVERSITY
发明人:
Keun Yong LEE,Eun Seok KO
申请号：
US16370319
公开号：
US20190298852A1
申请日:
2019.03.29
申请国别(地区):
US
年份:
2019
代理人:
摘要：
The present invention relates to a glycol chitosan-based hydrogel containing only natural polysaccharides without use of a toxic crosslinking agent. The hydrogel of the present invention exhibits a self-healing behavior under physiological conditions and in the presence of iron oxide nanoparticles, and thus can be useful for use as a delivery system for injection. In addition, in the hydrogel of the present invention, a delivery rate or amount of a substance carried within the hydrogel can be regulated using the magnetic field, which allows the hydrogel to be used for a variety of drug delivery and tissue engineering applications with on-demand release of gel payloads under external magnetic stimulation. The hydrogel can be effectively used as a delivery vehicle for a physiologically active substance such as a therapeutic agent.
