HYND, GEORGE,MACLEOD, CALUM,MANN, SAMUEL EDWARD,KULAGOWSKI, JANUSZ JOZEF,STANSFIELD, IAN,QUEROLLE, OLIVIER ALEXIS GEORGES,PONCELET, VIRGINIE SOPHIE,GROSS, GERHARD MAX,JACOBY, EDGAR,MEERPOEL, LIEVEN
申请号：
CA3066166
公开号：
CA3066166A1
申请日:
2018.07.04
申请国别(地区):
CA
年份:
2019
代理人:
摘要：
The present invention relates to pharmaceutical agents useful for therapy and/or prophylaxis in a mammal, and in particular to inhibitors of NF-?B-inducing kinase (NIK - also known as MAP3K14) useful for treating diseases such as cancer, inflammatory disorders, metabolic disorders and autoimmune disorders. The invention is also directed to pharmaceutical compositions comprising such compounds, and to the use of such compounds or pharmaceutical compositions for the prevention or treatment of diseases such as cancer, inflammatory disorders, metabolic disorders including obesity and diabetes, and autoimmune disorders.
