An injection device comprises a housing (5), an axially moveable dose delivery mechanism (10), an actuation button (20) for imparting movement to said delivery mechanism (10), and a dose setting arrangement (30) to select a dose volume. The dose setting arrangement (30) comprises a threaded member (31) arranged to engage a formation (9) on, or fixed relative to, the housing (5) such that axial movement relative to the housing (5) results in relative angular movement of the threaded member (31). The dose setting arrangement also includes a stop (9a) fixed relative to the housing, and arranged to cooperate with the threaded member (31) limiting axial movement thereof. Complementary engagement features (16, 36) are provided which are moveable between an engaged position in which relative axial movement of the delivery mechanism (10) and threaded member (31) is prevented and a disengaged position in which the threaded member (31) may be moved relative to the delivery mechanism (10) to adjust the dose. In use, forward movement of the actuation button (20) moves the engagement features (16, 36) into the engaged position.
