Provided are multi-wavelength phototherapy devices, systems and methods for the treatment of a disorder or disease, including multi-wavelength low level light therapy ("PBM"), in particular to multi-wavelength PBM and other phototherapy systems and methods for improving functionality in and/or restoring functionality to a cell and/or tissue through the coordinated and targeted delivery to the cell or tissue of two or more doses of light having distinct wavelengths, wherein the two or more doses of light, when delivered in a coordinated fashion, can stimulate the activity of two or more light sensitive factors that, when activated, provide and/or enhance a desired target cell functionality. Ophthalmic phototherapy devices, systems, and treatment methods to expose an eye to selected multi-wavelengths of light to promote the healing of damaged or diseased eye tissue. The devices include a housing having an interior an eyepiece disposed on the housing and configured and arranged for placement of an eye of the patient adjacent the eyepiece a first light source producing a first light beam having a first therapeutic wavelength and disposed within the housing a second light source producing a second light beam having a second therapeutic wavelength and disposed within the housing, where the second therapeutic wavelength differs from the first therapeutic wavelength by at least 25 nm.La présente invention concerne des dispositifs, des systèmes et des procédés de photothérapie à plusieurs longueurs donde pour le traitement dun trouble ou dune maladie, y compris une photothérapie de faible intensité (PBM) à plusieurs longueurs donde, et en particulier une PBM à plusieurs longueurs donde et dautres systèmes et procédés de photothérapie permettant daméliorer et/ou de restaurer la fonctionnalité dune cellule et/ou dun tissu par ladministration coordonnée et ciblée dans la cellule ou le tissu de deux doses de lumière ou davantage présentant des longueurs donde distinctes. Les deu
