Said Al-Jaroudi,Muhammad Altaf,Abdulaziz Al-Saadi,Anvarhusein Abdulkadir Isab
申请号：
US14850063
公开号：
US09481693B1
申请日:
2015.09.10
申请国别(地区):
US
年份:
2016
代理人:
摘要：
Gold(III) complexes with mixed ligands as anticancer agents. The gold(III) cations are coordinated to bidentate ligands having diamino functional groups: a diaminocyclohexane ligand and a 1,3-propylenediamine ligand. The diaminocyclohexane ligand can exist in both cis- and trans-configurations, resulting in isomeric gold(III) complexes. Also described are pharmaceutical compositions incorporating the gold(III) complexes, methods of synthesis, methods of treating cancer and methods of inhibiting cancer cell proliferation and inducing cancer cell apoptosis.
