The present invention is in the field of pyrimidine-based compounds for the treatment of disorders associated with abnormal cell proliferation, including but not limited to tumors and cancer. [Selected figure] Figure 3本発明は、腫瘍及び癌を含むが、これらに限定されない細胞増殖の異常に関係する障害の治療のためのピリミジン系化合物の分野にある。【選択図】図3