A system and method for analyzing population-based patient information is provided. The method includes the steps of data mining a plurality of patient records using a domain knowledge base relating to a disease of interest； compiling the mined data into a plurality of structured patient records； inputting at least one patient criteria relating to the disease of interest； and extracting at least one structured patient record matching the at least one patient criteria. The system includes a data miner for mining information from the plurality of patient records using a domain knowledge base relating to a disease of interest and for compiling the mined data into a plurality of structured patient records； an interface for inputting at least one patient criteria relating to the disease of interest； and a processor adapted for extracting at least one of the structured patient records matching the at least one patient criteria.
