METHODS FOR CONTROLLED PROLIFERATION OF STEM CELLS / GENERATING INNER EAR HAIR CELLS USING 3-(PYRIDIN-2-YL)-1H-INDOL-2-OL BASED COMPOUNDS

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专利权人:

发明人:

Christopher LOOSE,Will MCLEAN,Melissa HILL-DRZEWI

申请号：

US15447783

公开号：

US20170252348A1

申请日:

2017.03.02

申请国别(地区):

US

年份:

2017

代理人:

摘要：

The present invention relates to methods of inducing the self-renewal of stem/progenitor supporting cells, including inducing the stem/progenitor cells to proliferate while maintaining, in the daughter cells, the capacity to differentiate into hair cells. Specifically, the invention relates to methods of using compounds comprising a 3-(pyridin-2-yl)-1H-indol-2-ol containing moiety having a Formula I:and pharmaceutically acceptable salts thereof.

来源网站：

中国工程科技知识中心

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http://www.ckcest.cn/home/