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METHODS FOR CONTROLLED PROLIFERATION OF STEM CELLS / GENERATING INNER EAR HAIR CELLS USING 2-PYRIMIDINYLAMINOETHYLAMINO-2-PYRIDYL BASED COMPOUNDS
专利权人:
发明人:
Christopher LOOSE,Will MCLEAN,Melissa HILL-DRZEWI
申请号:
US15447763
公开号:
US20170252339A1
申请日:
2017.03.02
申请国别(地区):
US
年份:
2017
代理人:
摘要:
The present invention relates to methods of inducing the self-renewal of stem/progenitor supporting cells, including inducing the stem/progenitor cells to proliferate while maintaining, in the daughter cells, the capacity to differentiate into hair cells. Specifically, the invention relates to methods of using compounds comprising a 2-pyrimidinylaminoethylamino-2-pyridyl moiety having a Formula Iand pharmaceutically acceptable salts thereof.
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