SOLID COMPOSITION FOR CONTROLLED RELEASE OF IONIZABLE ACTIVE AGENTS WITH POOR AQUEOUS SOLUBILITY AT LOW PH AND METHODS OF USE THEREOF

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专利权人:

发明人:

RAMANI CHANDIR,WANG JUAN,KANE ANIL,CHOW KWOK,LAMBING JOE

申请号：

IN4161/DELNP/2011

公开号：

IN2011DN04161A

申请日:

2011.06.02

申请国别(地区):

IN

年份:

2012

代理人:

摘要：

(a) at least one active agent with a solubility of less than about 0.3 mg/ml in an aqueous solution with a pH of at most about 6.8 at a temperature of about 37°C and (b) a hydrophilic polymer matrix composition comprising

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