PROBLEM TO BE SOLVED: To provide skin injury healing accelerators in which injury in the skin can exert a healing acceleration effect even for full-thickness skin defect wound.SOLUTION: What containing a dectin-2 inhibitor, for example, an RNA having an RNA interference action specifically against mRNA encoding dectin-2 in a mammalian organism, or an expression vector thereof, is used as an accelerator for healing skin injury, since suppressing the expression of dectin-2 reduced inflammatory response, resulting in an accelerated level of skin injury healing and accelerated repair and regeneration of injured skin.SELECTED DRAWING: NoneCOPYRIGHT: (C)2020,JPO&INPIT【課題】皮膚における損傷が、全層欠損創に対しても治癒促進効果を発揮することができる、皮膚損傷治癒促進剤の提供。【解決手段】デクチン－２の発現を抑制すると、炎症応答が低下した結果、皮膚損傷治癒の進行レベルは促進し、損傷した皮膚の修復・再生が速まったことから、デクチン－２阻害剤、例えば、哺乳類生体内のデクチン－２をコードするｍＲＮＡに対して特異的にＲＮＡ干渉作用を有するＲＮＡ、又はその発現ベクターを含むものを、皮膚損傷治癒の促進剤とする。【選択図】なし
