A device for electroporating medicine-administration using hollow needle electrodes, comprising a medicine-administering head (1), a control panel, and a control wire and a tube (2) connecting the medicine-administering head (1) and the control panel; the medicine-administering head (1) comprises a universal joint (8), a camera (10), an illuminating lamp (11), a molecular medicine transport structure (13), an electric connector (14), a grill (9), a hollow needle electrode array (12), and a telescoping structure (15); the control panel comprises a display (7) for observing the video captured by the camera, a joystick (3) for controlling the universal joint (8), and a remote initiating device (a) for controlling the triggering of electric pulses; the control panel is connected to the electric connector (14) inside of the medicine-administering head (1) by means of the wires arranged inside of the tube (2). The device for electroporating medicine-administration provides real-time monitoring of the electroporation performance during cell electroporation, is universal and chemical pollution free, has good electroporating and cell-electroporating effects, reduces treatment time and harm to normal cells, enhances drug utilization rate, and accurately adjusts the strength and range of the electric field, thereby mitigating the pain a patient experiences during treatment.La présente invention concerne un dispositif d'administration de médicament par électroporation au moyen d'électrodes à aiguille creuse, comprenant une tête d'administration de médicament (1), un panneau de commande, et un fil de commande et un tube (2) reliant la tête d'administration de médicament (1) et le panneau de commande ; la tête d'administration de médicament (1) comprend une jonction universelle (8), une caméra (10), une lampe d'éclairage (11), une structure de transport de médicament moléculaire (13), un connecteur électrique (14), une grille (9), un réseau d'électrodes à aiguille creuse (12), et