Frédérique Brune,André Delhon,Jean Gardette,Jean François Patoiseau,Alain Marty,Etienne Severac
申请号:
US13159022
公开号:
US08227479B2
申请日:
2011.06.13
申请国别(地区):
US
年份:
2012
代理人:
摘要:
The present invention relates to a docosahexaenoic acid ester with an alcohol chosen among the group-B vitamins or provitamins, advantageously comprised by: nicotinyl alcohol of the following formula (I), panthenol of the following formula (II), and inositol of the following formula (III) or with isosorbide of the following formula (IV) or isosorbide mononitrate of the following formula (V). It also relates to a method of preparation of same, a pharmaceutical composition comprising same and the use of same in the treatment or prevention of cardiovascular disease, in particular auricular fibrillation.