JEAN PIERRE BLAREAU,MICHEL COLAVIZZA,FREDERIC HUGUET,CHARLES ROMOND,GIANNI FROIDEVAUX,JEAN FRANCOIS BOUDIER
申请号：
FR1055433
公开号：
FR2962134B1
申请日:
2010.07.05
申请国别(地区):
FR
年份:
2014
代理人:
摘要：
Preparing non separated macromolecular complex (totum) produced by bacteria belonging to the strain Bifidobacterium longum1-3994 comprises: (i) preparing culture medium having proteins/proteins derived from milk and lactose and/or hydrolyzed lactose, at least one antioxidant, optionally at least one pH regulator and/or at least growth factor； (ii) inoculating and incubating at a temperature of 25-39[deg] C, preferably 36-37[deg] C, in the strain； (iii) inactivating the bacteria obtained from the strain, present in the culture medium； and (iv) stabilizing the totum. Preparing non separated macromolecular complex (or totum) produced by bacteria belonging to the strain Bifidobacterium longum1-3994 comprises: (i) preparing culture medium comprising proteins or proteins derived from milk and lactose and/or hydrolyzed lactose, at least one antioxidant, optionally at least one pH regulator and/or at least growth factor； (ii) inoculating and incubating, at a temperature of 25-39[deg] C, preferably 36-37[deg] C, in a strain of Bifidobacterium longum1-3994； (iii) inactivating the bacteria obtained from Bifidobacterium longumstrain 1-3994 present in the culture medium； and (iv) stabilizing the totum. ACTIVITY : Antiarthritic. MECHANISM OF ACTION : None given.
