ALKAHEST INC.;THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY;U.S. GOVERNMENT as represented by THE DEPARTMENT OF VETERANS AFFAIRS;THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
Methods of treating an adult mammal for an aging-associated impairment are provided. Aspects of the methods include reducing the 2-microglobulin (B2M) level in the mammal in a manner sufficient to treat the mammal for the aging-associated impairment. A variety of aging-associated impairments may be treated by practice of the methods, which impairments include cognitive impairments.
