Fused bicyclic pyrimidine compounds as aurora kinase inhibitors

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专利权人:

Selvaraj Mohane Coumar;Tsu-An Hsu;Yu-Sheng Chao;Hsing-Pang Hsieh;Su-Ying Wu

发明人:

Hsing-Pang Hsieh,Selvaraj Mohane Coumar,Tsu-An Hsu,Su-Ying Wu,Yu-Sheng Chao

申请号：

US12428044

公开号：

US08138194B2

申请日:

2009.04.22

申请国别(地区):

US

年份:

2012

代理人:

摘要：

Fused bicyclic pyrimidine compounds of formula (I):wherein R1, R3, R4, X1, X2, Y, Z, A, B, C, D, n, and the two bonds are defined herein. Also disclosed are a method for inhibiting Aurora kinase activity and a method for treating cancer with these compounds.

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http://www.ckcest.cn/home/