CD40L-SPECIFIC TN3-derivative DIFFERENCES (SCAFFOLDS) AND THEIR PROMOTION METHODS

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专利权人:

Viela Bio; Inc.

发明人:

COYLE, Anthony,BACA, Manuel,THISTED, Thomas,DRABIC, Stacey,GRINBERG, Luba,NOVARRA, Shabazz,OGANESYAN, Vaheh,HERBST, Ronald,SPENCER, David, Kenneth

申请号：

DK12840074

公开号：

DK2771022T3

申请日:

2012.10.10

申请国别(地区):

DK

年份:

2020

代理人:

摘要：

The present invention provides Tenascin-3 FnIII domain-based scaffolds that specifically bind to CD40L. The invention further provides engineered variants with increased affinity for the target. The present invention is also related to engineered scaffolds as prophylactic, diagnostic, or therapeutic agents, in particular for therapeutic uses against SLE and other autoimmune diseases and conditions.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/