WALKER KENNETH W,GEGG COLIN V JR,HECHT RANDY I,BELOUSKI EDWARD JOHN,LI YUE-SHENG,MICHAELS MARK LEO,XU JING,ELLISON MURIELLE MARIE
申请号:
ZA201103356
公开号:
ZA201103356B
申请日:
2011.05.09
申请国别(地区):
ZA
年份:
2012
代理人:
摘要:
The invention provides nucleic acid molecules encoding FGF21 mutant polypeptides, FGF21 mutant polypeptides comprising extended in vivos half-lives, pharmaceutical compositions comprising FGF21 mutant polypeptides having extended in vivos half lives, and methods for treating metabolic disorders using such nucleic acids, polypeptides, or pharmaceutical compositions.