WALKER, Kenneth W.,GEGG, Colin, V., Jr.,HECHT, Randy I.,BELOUSKI, Edward J.,LI, Yue-Sheng,MICHAELS, Mark L.,XU, Jing,ELLISON, Murielle M.
申请号:
EP09748878
公开号:
EP2358749B1
申请日:
2009.10.08
申请国别(地区):
EP
年份:
2018
代理人:
摘要:
The invention provides nucleic acid molecules encoding FGF21 mutant polypeptides, FGF21 mutant polypeptides comprising extended in vivos half-lives, pharmaceutical compositions comprising FGF21 mutant polypeptides having extended in vivos half lives, and methods for treating metabolic disorders using such nucleic acids, polypeptides, or pharmaceutical compositions.