A method of detecting polymorphism in the ABCB1 gene associated with a lack of response for a CNS-active drug as well as a drug comprising an ABCB1 inhibitor for use in the treatment of CNS-related diseases

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专利权人:

MAX-PLANCK-GESELLSCHAFT ZUR FOERDERUNG DER WISSENSCHAFTEN E.V.

发明人:

HOLSBOER, FLORIAN,BINDER, ELISABETH,MUELLER-MYHSOK, BERTRAM,UHR, MANFRED

申请号：

DK05748517

公开号：

DK1756310T3

申请日:

2005.05.12

申请国别(地区):

DK

年份:

2013

代理人:

摘要：

The present invention relates to methods, compositions and kits for determining the prognosis of a clinical response in a human patient to a medicament which acts in the central nervous system and which is a substrate of the ABCB1 protein. Further, the invention relates to a combination of medicaments for the treatment of human patients having specific polymorphisms in the ABCB1 gene.

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中国工程科技知识中心

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