The present invention relates to the use of selective adenosine A1 agonists, in particular the dicyanopyridines of formula (I), for the treatment and/or prophylaxis of glaucoma and ocular hypertension as well as the their use for the production of a medicament for the treatment and/or prophylaxis of glaucoma and ocular hypertension.本發明係關於選擇性腺苷A1促效劑,特言之式(I)之二氰基吡啶,用於治療及/或預防青光眼和高眼壓症之用途,以及其用於製造醫藥品供治療及/或預防青光眼和高眼壓之用途。