The Board of Regents of the University of Texas System
发明人:
Jef DE BRABANDER,Luis F. PARADA,S. Kyun LIM,Qiren LIANG,Hua-yu WANG,Yufeng SHI
申请号:
US16060913
公开号:
US20180354909A1
申请日:
2016.12.09
申请国别(地区):
US
年份:
2018
代理人:
摘要:
Provided herein are compounds of the formula:(I) wherein: R1, R2, R3, R4, R5, X, A1, A2, A3, and A4 are as defined herein. In some aspects, these compounds may be used to treat cancer and other hyperproliferative disease. In some aspects, compositions, methods of treatment, and methods of synthesis are also provided herein.