A surgical instrument that includes a motor-powered drive unit that drives a portion of a firing member assembly in an axial direction to actuate a surgical end effector coupled to the instrument. The instrument may further include a retraction system configured to interact with the firing member assembly to permit a clinician to manually retract the portion of the firing member assembly should it become jammed or inadvertently stopped during a firing process. The surgical instrument includes a locking arrangement that interfaces with the retraction system and the motor-powered drive unit to prevent the transfer of the retraction forces generated by the retraction system to the motor shaft without physically separating portions of the motorized drive unit.
