您的位置: 首页 > 农业专利 > 详情页

Process for making particles for delivery of drug nanoparticles
专利权人:
Wenhao Chen;Jun Hu;Jiyao Zhang;Zhigang Shen;Lingyan Gao;Zhe Wang;William Glover;Jian Feng Chen;Nital Arvind Jugade;Jimmy Sung Lai Yun
发明人:
Zhigang Shen,Jimmy Sung Lai Yun,Jun Hu,Nital Arvind Jugade,Jiyao Zhang,Wenhao Chen,Zhe Wang,Lingyan Gao,William Glover,Jian Feng Chen
申请号:
US13120146
公开号:
US08835376B2
申请日:
2009.09.24
申请国别(地区):
US
年份:
2014
代理人:
摘要:
A process for making particles for delivery of drug nanoparticles is disclosed herein. The process comprises the steps of (a) forming a suspension of drug nanoparticles by mixing a precipitant solution with an anti-solvent solution under micro-mixing environment, where the formed nanoparticles have a narrow particle size distribution; (b) providing an excipient to at least one of the precipitant solution, the anti-solvent solution and the suspension of drug nanoparticles, the excipient being selected to maintain said drug nanoparticles in a dispersed state when in liquid form; and (c) drying the suspension of drug nanoparticles containing the excipient therein to remove solvent therefrom, wherein removal of the solvent causes the excipient to solidify and thereby form micro-sized matrix particles, each micro-sized particle being comprised of drug nanoparticles dispersed in a solid matrix of the excipient.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

意 见 箱

匿名:登录

个人用户登录

找回密码

第三方账号登录

忘记密码

个人用户注册

必须为有效邮箱
6~16位数字与字母组合
6~16位数字与字母组合
请输入正确的手机号码

信息补充