A medical article securement device 100 holds a medical article 300 such as a catheter hub or a connector fitting in position upon the body of a patient and inhibits movement of the medical article relative to the patient. The medical article 300 includes an elongated body 430, a pair of outwardly extending wings 301(a), 301(b), and a port 305. The securement device 100 includes a retainer 120 and at least one anchor pad 110. The retainer 120 forms a channel 140 into which at least a portion of the medical article 300 is secured. The retainer 120 includes at least one abutment that abuts against a contact point or surface on the port 305. The anchor pad 110 includes an adhesive layer that is attached to both an epidural layer of a patient and at least a portion of the pair of wings 301(a), 301(b).