VACCIN CONJUGUÉ DE PEPTIDE D'ANTIGÈNE WT1

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专利权人:

INTERNATIONAL INSTITUTE OF CANCER IMMUNOLOGY, INC.; LTD.;SUMITOMO DAINIPPON PHARMA CO., LTD.;SUMITOMO DAINIPPON PHARMA CO.

发明人:

LI, CHIANG JIA,BAN, HITOSHI,NISHIO, YUKIHIRO,GOTO, MASASHI,NISHIHARA, TOSHIO,TAKANASHI, YOSUKE

申请号：

EP14775899

公开号：

EP2982681A4

申请日:

2014.03.28

申请国别(地区):

EP

年份:

2016

代理人:

摘要：

The present invention provides a compound represented by the formula (1): wherein X a and Y a are each a single bond and the like, cancer antigen peptide A is an MHC class I-restricted WT1 peptide consisting of 7 - 30 amino acid residues, R 1 is a hydrogen atom, a group represented by the formula (2): wherein X b and Y b are each a single bond and the like, cancer antigen peptide B has a sequence different from that of the cancer antigen peptide A, and is an MHC class I-restricted WT1 peptide consisting of 7 - 30 amino acid residues, or cancer antigen peptide C, and cancer antigen peptide C has a sequence different from that of the cancer antigen peptide A, and is an MHC class I-restricted WT1 peptide or an MHC class II-restricted WT1 peptide, consisting of 7 - 30 amino acid residues containing one cysteine residue, or a salt thereof, and the like.

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