INHIBITORS OF HISTONE DEMETHYLASES

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专利权人:

EPITHERAPEUTICS APS

发明人:

LABELLE, MARC,BOESEN, THOMAS,KHAN, QASIM,VAKITI, RAMKRISHNA REDDY,SHARMA, UTPAL,YANG, YING,MEHROTRA, MUKUND,SARASWAT, NEERJA,ULLAH, FARMAN

申请号：

PH12015501868

公开号：

PH12015501868A1

申请日:

2015.08.25

申请国别(地区):

PH

年份:

2015

代理人:

摘要：

Compounds of the form In which Q is selected from -CH=NR12, -W, -CH=2NHR13, -CH=O and -CH(OR17)2 capable of modulating the activity of histone demethylases (HDMEs), which are useful for prevention and/or treatment of diseases in which genomic dysregulation is involved in the pathogenesis, such as e.g. cancer and formulations and methods of use of such compounds.

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