GANLOV, KARIN,OSTBERG, MAGNUS,LINDBERG, PER L.,GUSTAVSSON, BENGT,SUNDEN, GUNNEL E.
申请号：
CA3087514
公开号：
CA3087514A1
申请日:
2019.01.04
申请国别(地区):
CA
年份:
2019
代理人:
摘要：
The present invention provides methods for treating patients diagnosed with colorectal cancer and metastatic colorectal cancers in a chemotherapeutic regimen comprising the administration of [6R]-5,10-methylene tetrahydrofolate (6R-MTHF), 5-fluorouracil (5-FU), bevacizumab, and oxaliplatin. The methods reduce disease progression and provide improved overall response rates compared to standard treatments with other folates such as folinic acid.
